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Laparoscopic-Assisted Abdominoperineal Resection for Primary Anorectal Malignant Melanoma: A Case Report of a Rare Disease

Dae Ro Lim, Jung Cheol Kuk, Taehyung Kim, Hee Kyung Kim, Eung Jin Shin

Med Sci Case Rep 2018; 5:36-40

DOI: 10.12659/MSCR.910464

Available online: 2018-05-20

Published: 2018-05-20


#910464

BACKGROUND: Malignant melanomas usually occur in the skin, retina, head, and neck regions. Anorectal malignant melanoma is a very rare colorectal disease, accounting for only 1–2% of all lower gastrointestinal cancer, 0.2–3% of all melanomas, and 4% of all anal malignancies. The correct diagnosis is confirmed using a combination of immunohistochemical stains for melanocytic differentiation, such as S-100, HMB-45, Melan-A, and tyrosinase.
CASE REPORT: We report the case of a 76-year-old South Korean woman with primary anorectal malignant melanoma confirmed after a laparoscopic-assisted abdominoperineal resection. She had a palpable anorectal mass 2.5 cm from the anal verge. No distant metastasis was found. The mass was a well-demarcated fungating mass (3.7×2.3×1.7 cm) in the anorectum. A histological examination showed a nesting or trabecular pattern of the epithelioid cells without melanin deposition. Immunohistochemical staining revealed that the tumor cells were positive for S-100 protein, Melan-A, and vimentin, confirming the primary anorectal amelanotic melanoma diagnosis.
CONCLUSIONS: Our patient underwent laparoscopic-assisted abdominoperineal resection to treat a rare anorectal malignant melanoma.

Keywords: Colorectal Surgery, Laparoscopy



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