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Management of Infective Endocarditis by Extended-Spectrum β-Lactamase (ESBL)-Producing Enterobacter Cloacae

Marcelo Cruzalegui, Sebastián Shu, Juan Ruiz, Michèle Panduro, Félix Medina-Palomino

(Alberto Hurtado Department of Medicine, Peruana Cayetano Heredia University, Lima, Peru)

Med Sci Case Rep 2017; 4:45-49

DOI: 10.12659/MSCR.903163

BACKGROUND: Gram-negative bacteria are rarely the cause of infective endocarditis, especially in patients without cardiovascular risk factors. To our knowledge, only 30 cases due to Enterobacter cloacae have been reported in the literature and 1 was suspected of producing extended-spectrum β-lactamases.
CASE REPORT: We present a patient with extended-spectrum β-lactamase-producing Enterobacter cloacae infective endocarditis. The patient underwent surgery to replace the affected valve, is being treated with meropenem and amikacin, and currently has a favorable course.
CONCLUSIONS: We review past cases and discuss the need for surgical intervention and dual antibiotic therapy according to current guidelines and evidence.

Keywords: Endocarditis, Enterobacter cloacae, Gram-Negative Bacteria

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
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